SimAbs is a biotechnology company based in Diepenbeek, Belgium, focused on developing and applying continuous manufacturing technologies for biologics production. Founded in 2019, the company operates from the BioVille life sciences campus and works with biopharmaceutical companies to develop and manufacture therapeutic antibodies and other complex biologics.

The company has developed an integrated manufacturing platform built around continuous bioprocessing, designed to provide faster, flexible and cost-efficient production compared with traditional batch manufacturing systems. This platform enables the development and production of monoclonal antibodies and other complex biologics in quantities ranging from milligrams to kilograms, supporting projects from early development through manufacturing.

SimAbs positions its platform as a solution to improve productivity, maintain consistent product quality and reduce the overall cost of biologics manufacturing. The company’s approach integrates upstream and downstream processing in a continuous production environment, helping biopharmaceutical companies accelerate development timelines while maintaining regulatory and quality standards.

Key Products and Services

Continuous Bioprocessing Platform

• Integrated manufacturing platform based on continuous bioprocessing for antibody production.
• Designed to improve production speed, consistency and cost efficiency compared with traditional batch processes.

Cell Line Development

Proprietary technology for developing stable recombinant protein-producing cell lines using CHO cells in continuous perfusion systems.

Process Development

Development of scalable continuous bioprocesses to support biologics manufacturing and accelerate time to market.

Biologics Manufacturing (GMP)

GMP manufacturing services for biologics and recombinant proteins, including antibody production for clinical or commercial applications.

Additional Development and Support Services

• Analytical and formulation development
• Technology transfer to GMP production
• Quality management and validation
• Regulatory support and project management
• Clinical research support services

SimAbs focuses on advancing continuous manufacturing technologies to support the efficient production of therapeutic biologics. By combining cell line development, process development and GMP manufacturing within an integrated platform, the company aims to help biopharmaceutical partners bring complex antibody therapies to market more quickly and cost-effectively while supporting the broader shift toward more sustainable and flexible biomanufacturing models.