Grünenthal PRO operates as the contract manufacturing arm of Grünenthal, offering comprehensive support across the pharmaceutical value chain—from active substance production to finished product solutions. With five vertically integrated manufacturing sites across Europe and Latin America (Germany, Switzerland, Italy, Ecuador, Chile), the company supports global pharmaceutical and biopharmaceutical customers through robust supply capabilities, specialised technologies, and regulatory expertise.

Grünenthal PRO combines efficient production with consistently high service levels. The organisation emphasizes client satisfaction by tailoring operations to meet diverse needs, underpinned by the long-term commitment typical of its family-owned heritage.

Key Products & Services

Contract Manufacturing Services (CMO):

• End-to-end pharmaceutical assembly, packaging and labelling, including controlled substances and advanced automation capabilities.
• Regulatory services, controlled drug handling and production process design, supporting exports to approximately 100 countries.
• Biopharma assembly and packaging, especially for injectable therapies including pre-filled syringes, pens, autoinjectors, kit-packaging, cold-storage and release testing.

Pharmaceutical Packaging Solutions:

• Primary and secondary packaging across formats such as blisters (PVC, PVDC, Aclar, alu-alu), patches, sachets, wallets, sticks, bottles (glass/plastic), envelopes, plus serialisation and aggregation.

API Production:

• Manufacture of key active pharmaceutical ingredients, including tramadol, betahistine and oxatomide, through highly automated facilities. In 2024, Grünenthal PRO supplied some 390 tonnes of APIs to over 50 customers, delivering approximately one-third of global tramadol output.

Bulk Production:

• Manufacturing of solid, semi-solid and liquid formulations

Special Technologies & Regional Centres of Excellence:

• Hormone production in Chile (women’s health products).
• Unit-dose nasal spray filling and packaging from Italy.

Grünenthal PRO stands as a trusted, global contract manufacturing partner for pharmaceutical and biotech clients seeking rigorous quality, modular production capabilities, and flexible service offerings. With an integrated network of modern production facilities, deep experience in API and formulation manufacturing, and a robust packaging and biopharma service portfolio, the company is well positioned to help customers bring safe and reliable medicines to market efficiently and effectively.