Single Cell Discoveries is a specialist contract research organisation (CRO) providing advanced transcriptomics and multiomics services to pharmaceutical, biotechnology and academic research organisations.

Headquartered in Utrecht, the Netherlands, the company supports clients across the full transcriptomics workflow, from experimental design and sample preparation through sequencing, bioinformatics and data interpretation. Its technology-agnostic approach allows researchers to select the most appropriate methodology for their biological question rather than being restricted to a single sequencing platform.

Single Cell Discoveries provides services across single-cell RNA sequencing, spatial transcriptomics, bulk RNA sequencing and multiomics, supporting applications throughout drug discovery, translational research and preclinical development.

Services and Capabilities

The company provides a broad portfolio of transcriptomics services, including:

• Single-cell RNA sequencing
• Spatial transcriptomics
• Bulk RNA sequencing
• Multiomics
• High-throughput transcriptomics
• Custom assay development
• Sample preparation and processing
• Sequencing
• Bioinformatics analysis
• Data interpretation and scientific support

Single Cell Discoveries works with a range of established technologies, including 10x Genomics, Parse Biosciences, Scale Biosciences, SORT-seq, VASA-seq and Visium HD.

Its internal research and development capabilities also enable customised workflows to be developed for projects where standard commercial approaches may not adequately address the scientific requirements.

Therapeutic and Research Applications

Single Cell Discoveries supports pharmaceutical and biotechnology research programmes across areas including:

• Target discovery and validation
• Drug screening
• Mechanism-of-action studies
• Biomarker discovery
• Immunology and immune profiling
• Immuno-oncology
• Neuroscience
• Cell and gene therapy
• Translational research
• Preclinical research

The company has experience working with complex and low-input biological samples and with samples derived from a wide range of species and tissue types.

Bioinformatics and Data Analysis

Single Cell Discoveries provides integrated bioinformatics support alongside its laboratory services, helping clients convert sequencing output into interpretable biological insights.

Projects can include data processing, quality control, statistical analysis, visualisation and biological interpretation, allowing pharmaceutical and biotechnology teams to receive analysed datasets rather than raw sequencing data alone.

Technology and Scientific Expertise

Single Cell Discoveries operates a technology-agnostic model, enabling different sequencing platforms and methodologies to be selected according to project requirements.

The company is a certified 10x Genomics service provider and combines specialist laboratory expertise with bioinformatics and scientific consultancy to support complex transcriptomics studies.

Its capabilities span more than 50 species and numerous tissue types, making the company suitable for both established research programmes and projects involving less conventional biological models.