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Horizon Scanning: Bridging the $300bn Revenue Gap as Pharma Faces Patent Cliff

“The pharma industry has a looming revenue gap. We’ve estimated $300 billion of pharma revenue at risk from loss of exclusivity over the next five years,” warns Jeff Holder, Partner at L.E.K. Consulting. Adam Siebert and Jeff Holder are partners

2 December 2024

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!important;}:root{--directorist-color-primary:#444752;--directorist-color-primary-rgb:68,71,82;--directorist-color-secondary:#f2f3f5;--directorist-color-secondary-rgb:242,243,245;--directorist-color-dark:#000;--directorist-color-dark-rgb:0,0,0;--directorist-color-success:#28a800;--directorist-color-success-rgb:40,168,0;--directorist-color-info:#2c99ff;--directorist-color-info-rgb:44,153,255;--directorist-color-warning:#f28100;--directorist-color-warning-rgb:242,129,0;--directorist-color-danger:#f80718;--directorist-color-danger-rgb:248,7,24;--directorist-color-white:#fff;--directorist-color-white-rgb:255,255,255;--directorist-color-body:#404040;--directorist-color-gray:#bcbcbc;--directorist-color-gray-rgb:188,188,188;--directorist-color-gray-hover:#bcbcbc;--directorist-color-light:#ededed;--directorist-color-light-hover:#fff;--directorist-color-light-gray:#808080;--directorist-color-light-gray-rgb:237,237,237;--directorist-color-deep-gray:#808080;--directorist-color-bg-gray:#f4f4f4;--directorist-color-bg-light-gray:#f4f5f6;--directorist-color-bg-light:#ededed;--directorist-color-placeholder:#6c757d;--directorist-color-overlay:rgba(var(--directorist-color-dark-rgb),.5);--directorist-color-overlay-normal:rgba(var(--directorist-color-dark-rgb),.2);--directorist-color-border:#e9e9e9;--directorist-color-border-gray:#d9d9d9;--directorist-box-shadow:0 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#directorist.atbd_wrapper .widget.atbd_widget .atbd_badge.atbd_badge_featured i::after,.directorist-listing-single .directorist-badge.directorist-badge-featured i::after{background:var(--directorist-color-featured-badge) !important;}.atbd_bg-badge-popular i::after,.atbd_content_active #directorist.atbd_wrapper .atbd_badge.atbd_badge_popular i::after,.atbd_content_active .widget.atbd_widget[id^=bd] .atbd_badge.atbd_badge_popular i::after,.atbd_content_active .widget.atbd_widget[id^=dcl] .atbd_badge.atbd_badge_popular i::after,.atbd_content_active #directorist.atbd_wrapper .widget.atbd_widget .atbd_badge.atbd_badge_popular i::after,.directorist-listing-single .directorist-badge.directorist-badge-popular i::after{background:var(--directorist-color-popular-badge) !important;}.atbd_content_active #directorist.atbd_wrapper .atbd_badge.atbd_badge_new,.directorist-listing-single .directorist-badge.directorist-badge-new i::after{background:var(--directorist-color-new-badge) 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!important;}:root{--directorist-color-primary:#444752;--directorist-color-primary-rgb:68,71,82;--directorist-color-secondary:#f2f3f5;--directorist-color-secondary-rgb:242,243,245;--directorist-color-dark:#000;--directorist-color-dark-rgb:0,0,0;--directorist-color-success:#28a800;--directorist-color-success-rgb:40,168,0;--directorist-color-info:#2c99ff;--directorist-color-info-rgb:44,153,255;--directorist-color-warning:#f28100;--directorist-color-warning-rgb:242,129,0;--directorist-color-danger:#f80718;--directorist-color-danger-rgb:248,7,24;--directorist-color-white:#fff;--directorist-color-white-rgb:255,255,255;--directorist-color-body:#404040;--directorist-color-gray:#bcbcbc;--directorist-color-gray-rgb:188,188,188;--directorist-color-gray-hover:#bcbcbc;--directorist-color-light:#ededed;--directorist-color-light-hover:#fff;--directorist-color-light-gray:#808080;--directorist-color-light-gray-rgb:237,237,237;--directorist-color-deep-gray:#808080;--directorist-color-bg-gray:#f4f4f4;--directorist-color-bg-light-gray:#f4f5f6;--directorist-color-bg-light:#ededed;--directorist-color-placeholder:#6c757d;--directorist-color-overlay:rgba(var(--directorist-color-dark-rgb),.5);--directorist-color-overlay-normal:rgba(var(--directorist-color-dark-rgb),.2);--directorist-color-border:#e9e9e9;--directorist-color-border-gray:#d9d9d9;--directorist-box-shadow:0 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