- Onyx Scientific has expanded its solid form and materials science screening capabilities, with new investments planned through early 2026.
- The upgrade targets complex molecules, particularly DCS class II and IV compounds, and supports development from early phase through to commercial supply.
Onyx Scientific has announced the expansion of its solid form and materials science screening capabilities in 2026, following the company’s 25th anniversary at the end of 2025. The investment is aimed at supporting flexible, phase-appropriate development programmes for complex molecules.
The expansion responds to increasing demand for integrated crystallisation development, particle engineering and preformulation support across early and late development stages. The company said the enhanced offering is particularly relevant for compounds classified as Developability Classification System (DCS) class II and IV, where solid-state properties can present development challenges.
A central addition to the toolkit is the Technobis Crystalline PV/RR Line, which combines temperature and turbidity measurements with in-line particle imaging. The platform enables real-time visualisation of crystallisation behaviour and slurry conversions at high resolution, supporting more detailed understanding of nucleation and solid form evolution.
“With added capacity for real-time particle insight, we can now guide clients with more confidence through early-phase material selection and optimization.”
Chris Atherton, Commercial Director at Onyx Scientific
Alongside the crystal screening platform, Onyx has added new spray-drying, lyophilisation and jet milling systems to support preparation of small- and large-scale engineering batches. The company said these capabilities strengthen its solid-state offering within its CDMO and contract manufacturing services, enabling tailored material generation for performance testing, partner studies and progression towards commercial development.
