Ennolys, a business unit of the Lesaffre Group, has more than 30 years of experience in industrial fermentation. Based in Soustons in southwest France, the company supports biotechnology, food, nutraceutical, cosmetics, agriculture, animal nutrition and health applications. Its CDMO/CMO division helps customers move microbial processes from pilot development through industrial and commercial production.

The company provides an integrated approach covering fermentation, downstream processing (DSP), drying, quality management, technology transfer and industrial scale-up. Its fermentation capabilities cover batch and fed-batch processes and a broad range of microorganisms, including bacteria, yeasts, filamentous fungi and microalgae. Ennolys has more than 200,000 litres of fermentation capacity across vessels ranging from 100 litres to 50,000 litres.

Key products and services

Bioprocess development and optimisation – R&D, process development and analytical support.
Fermentation services – Batch, fed-batch, aerobic and anaerobic fermentation across different microbial strains.
Downstream processing (DSP) – Purification, filtration, concentration, extraction, crystallisation and separation processes.
Drying services – Lyophilisation and spray drying.
Technology transfer and industrial scale-up – Process optimisation, pilot trials, analytical validation and transfer to industrial production.
CDMO/CMO services – Contract fermentation and end-to-end process industrialisation from pilot scale through commercial production.
Natural aromatic molecules – Fermentation-derived molecules including natural acetaldehyde, gamma-octalactone, gamma-decalactone and organic acids.
Natural flavours – Natural flavour ingredients and solutions for food and other applications.

With its combination of fermentation expertise, industrial infrastructure and integrated downstream capabilities, Ennolys provides customers with a pathway from bioprocess development through scale-up and industrial production. Its services are designed to support the development and industrialisation of microbial processes while providing flexibility across applications and production requirements.