Wheeler Bio

Wheeler Bio is an innovative biomanufacturing company dedicated to expediting the translation of therapeutic discoveries into clinical applications. By integrating seamlessly with pre-clinical discovery processes, Wheeler Bio offers rapid, high-quality biomanufacturing services through its Modular CMC platform. ​

Founded by a team of industry experts and strategic investors, Wheeler Bio addresses the need for a novel contract development and manufacturing organisation (CDMO) model to assist innovators in achieving their clinical milestones more efficiently. The company's unique hub-and-spoke operational model, centred in Oklahoma City, integrates with biotechs and discovery contract research organisations (CROs), aiming to revolutionise the speed of drug development. ​

Wheeler Bio's lead service offering, Portable CMC™, functions as the industry's first "CMC middleware," effectively bridging the gap between discovery and clinical manufacturing. This platform simplifies the path from drug discovery to first-in-human trials, providing innovators with increased momentum during technology transfer, shorter timelines, reduced risk, and lower costs. ​

Key Products and Services:

Custom Development Services:

• Transient Protein Expression
• Cell Line Development​
• Process Development and Optimisation
• ​Analytical Development and Qualification​
• Process Characterisation​
• Technology Transfer​
• Toxicology Material Supply
• Formulation Development

GMP Services:

• cGMP Drug Substance Manufacturing
• cGMP Master Cell Banking

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​Wheeler Bio's state-of-the-art manufacturing centre, located within the "Ziggurat" building in downtown Oklahoma City, encompasses 35,000 square feet of dedicated cGMP clean-room space. The facility features an open ballroom design, closed-process, and digitally connected equipment, ensuring maximum flexibility, transparency, and speed in biomanufacturing processes. ​cGMP Master Cell Banking

Wheeler Bio is committed to transforming the biomanufacturing landscape by providing agile, integrated solutions that accelerate the development of innovative therapeutics. Through strategic collaborations, cutting-edge technologies, and a dedication to transparency, Wheeler Bio empowers clients to navigate the complex journey from discovery to clinical impact with greater efficiency and confidence.