PSI CRO Partners with Appian to Deploy AI-Powered Clinical Trial Site Selection Platform

• PSI CRO, a global full-service contract research organization employing more than 3,500 people across 58 countries, and Appian (Nasdaq: APPN), an enterprise AI automation technology provider, announced a strategic partnership on October 28, 2026, launching their first jointly developed AI-powered process orchestration solution to automate clinical trial site identification and selection across therapeutic areas and geographies.

• The live solution integrates Appian’s AI and process automation technology with PSI’s existing systems and data warehouse, enabling automated document processing, centralized workflow coordination, and real-time operational visibility. The partnership aims to improve site selection accuracy, reduce non-enrolling trial sites and patient recruitment delays, and establish a scalable platform for future AI-driven automation across the clinical trial lifecycle. 

PSI CRO, a global full-service contract research organization (CRO), and Appian (Nasdaq: APPN), a provider of enterprise AI automation technology, announced on October 28, 2026, a strategic partnership to advance AI-driven clinical trial operations. The collaboration has launched its first joint solution, an AI-powered process orchestration platform designed to automate clinical trial site identification and selection across multiple therapeutic areas, indications, and geographic regions.

The newly launched solution represents the first phase of a broader partnership to integrate AI, automation, and process orchestration across the clinical trial lifecycle. By connecting previously fragmented and manual site selection activities within a unified digital workflow, the companies aim to improve operational efficiency, transparency, and decision-making throughout clinical study planning and execution.

Clinical trial site selection involves coordinating multiple stakeholders, evaluating investigator sites, reviewing extensive documentation, and managing parallel processes across countries and regions. The Appian-powered solution consolidates these activities into a single digital system, covering project initiation through subsequent stages of site identification and selection.

The platform combines AI-enabled information processing with process orchestration capabilities to coordinate activities between clinical operations teams, automate documentation workflows, manage task routing and exceptions, and provide real-time visibility into operational performance. Rather than automating individual administrative tasks in isolation, the system connects people, data, and technology across the broader site selection process.

The solution integrates directly with PSI’s existing core systems and data warehouse alongside Appian’s AI and process intelligence technologies. This architecture is intended to support faster site evaluation, more consistent decision-making, and improved coordination between teams working across different countries and therapeutic programs.

“The AI-powered clinical trial site selection solution is an important step in how we are rethinking and connecting our operational processes.”

Kirill Soldatov, Head of Process Improvement at PSI CRO